Authors: James A. Winkelmann, Aya Eid, Graham Spicer, Luay M. Almassalha, The-Quyen Nguyen, Vadim Backman
Summary: Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
Source: Light: Science & Applications, 2019; 8 (1)