Authors:
Chiara Paviolo, James W. M. Chon, and Andrew H. A. Clayton
Summary:
Gold nanoparticles are functionalized with epidermal growth factor (EGF) molecules and incubated with HeLa cells. These new complexes mechanically interfere with the activation of EGF receptors in a length-dependent manner. Protein-functionalized gold nanoparticles hold great potential for unveiling the fundamental characteristics of cell receptors and for future pharmacological studies on receptor targeting.
Source:
Small; (12/12/14)