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Regenerative Medicine Journal

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells Genetic variation and neuroimaging measures in Alzheimer disease Self-assembly of three-dimensional prestressed tensegrity structures from DNA A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradation An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b Lipid-coated nano-calcium-phosphate (LNCP) for gene delivery Vortex-assisted DNA delivery Phosphorylation stabilizes Nanog by promoting its interaction with Pin1 A recessive screen for genes regulating hematopoietic stem cells Increased osteoarthritis in moose from Isle Royale Ecology of arthritis A thin film detection/response system for pathogenic bacteria Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus Reconstituting organ-level lung functions on a chip Melanocytes are deficient in repair of oxidative DNA damage and UV-induced photoproducts The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance Intergroup randomized phase III study of androgen deprivation therapy (ADT) plus radiation therapy (RT) in locally advanced prostate cancer (CaP) (NCIC-CTG, SWOG, MRC-UK, INT: T94-0110; NCT00002633). Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa A distinctive role for focal adhesion proteins in three-dimensional cell motility Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas Antimethicillin-resistant Staphylococcus aureus (MRSA) activity of 'pacific propolis' and isolated prenylflavanones Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists Diabetes depresses synaptic transmission in sympathetic ganglia by inactivating nAChRs through a conserved intracellular cysteine residue A coding-independent function of gene and pseudogene mRNAs regulates tumour biology Single-cell NF-κB dynamics reveal digital activation and analogue information processing Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy Serotonin regulates pancreatic beta cell mass during pregnancy Engineered allosteric activation of kinases in living cells Human amnion epithelial cell transplantation abrogates lung fibrosis and augments repair Tissue-engineered lungs for in vivo implantation Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition Umpolung reactivity in amide and peptide synthesis Multiple epigenetic modifiers induce aggressive viral extinction in extraembryonic endoderm stem cells Gene therapy for type 1 diabetes: a combinatorial approach using neurogenin-3-interleukin-10 hepatic gene transfer reverses diabetes in overtly diabetic NOD mice Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer Tissue-engineered lungs for in vivo implantation Regeneration and orthotopic transplantation of a bioartificial lung Reconstructing the lung Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Functionally defective germline variants of sialic acid acetylesterase in autoimmunity Influenza A virus-generated small RNAs regulate the switch from transcription to replication Functional impact of global rare copy number variation in autism spectrum disorders Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations Reprogramming of T cells to natural killer–like cells upon Bcl11b deletion Dental pulp cells for induced pluripotent stem cell banking RNA-based gene therapy for HIV with lentiviral vector–modified CD34+ cells in patients undergoing transplantation for AIDS-related lymphoma The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2 Transposable elements have rewired the core regulatory network of human embryonic stem cells Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome Designing communicating colonies of biomimetic microcapsules Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome In vivo targeting of B-cell lymphoma with glycan ligands of CD22 Phase II trial of daily, oral green tea extract in patients with asymptomatic, Rai stage 0-II chronic lymphocytic leukemia (CLL) Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells A phase III random assignment trial comparing percutaneous hepatic perfusion with melphalan (PHP-mel) to standard of care for patients with hepatic metastases from metastatic ocular or cutaneous melanoma Permanently blocked stem cells derived from breast cancer cell lines Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2 Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4 A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy Functional impact of global rare copy number variation in autism spectrum disorders Regulation of microRNA expression and abundance during lymphopoiesis Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial Effective, broad spectrum control of virulent bacterial infections using cationic DNA liposome complexes combined with bacterial antigens Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications Identification of a B cell signature associated with renal transplant tolerance in humans Detection of femtomole quantities of mature cathepsin K with zymography Relationship between nucleosome positioning and DNA methylation Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase Three-dimensional early retinal progenitor 3D tissue constructs derived from human embryonic stem cells Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis GJC2 missense mutations cause human lymphedema Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955-2007 Tissue-engineered lungs for in vivo implantation An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression CD95 promotes tumour growth Phase I study of anti-CD25 mab daclizumab to deplete regulatory T cells prior to telomerase/survivin peptide vaccination in patients (pts) with metastatic breast cancer (MBC) A phase I study of CD40 agonist monoclonal antibody (CP-870,893) with gemcitabine in pancreatic cancer A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci Gazing into a crystal ball to predict kidney transplant outcome Identification of a B cell signature associated with renal transplant tolerance in humans Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans A molecular classifier for predicting future graft loss in late kidney transplant biopsies Directing astroglia from the cerebral cortex into subtype specific functional neurons Endothelial nitric oxide synthase deficiency causes collateral vessel rarefaction and impairs activation of a cell cycle gene network during arteriogenesis Micro-masonry: construction of 3D structures by microscale self-assembly Nanofiber assembly by rotary jet-spinning Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cues Common variation in ISL1 confers genetic susceptibility for human congenital heart disease PediaFlow maglev ventricular assist device: a prescriptive design approach Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis Gait biomechanics, spatial and temporal characteristics, and the energy cost of walking in older adults with impaired mobility A prospective U.S. ovarian cancer screening study using the risk of ovarian cancer algorithm (ROCA) A randomized phase II trial comparing exemestane, letrozole, and anastrozole in postmenopausal women with clinical stage II/III estrogen receptor-positive breast cancer Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells Loss of type III transforming growth factor-β receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript Prothymosin-α inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs Derivation of pre-x inactivation human embryonic stem cells under physiological oxygen concentrations Creation of a bacterial cell controlled by a chemically synthesized genome Autophagy as a therapeutic target in cancer treatment Indoor tanning and risk of melanoma: a case-control study in a highly exposed population Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes An autophagy-enhancing drug promotes degradation of mutant α1-antitrypsin z and reduces hepatic fibrosis Porcine induced pluripotent stem cells produce chimeric offspring Differential modeling of Fragile X Syndrome by human embryonic stem cells and induced pluripotent stem cells Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs A microarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice Retinal glial cells enhance human vision acuity A family history of type 2 diabetes increases risk factors associated with overfeeding A pathobiont of the microbiota balances host colonization and intestinal inflammation Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis Permanently blocked stem cells derived from breast cancer cell lines rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters Human CD34+ cells in experimental myocardial infarction. long-term survival, sustained functional improvement, and mechanism of action Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cues A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth Stem cell transplantation in multiple sclerosis: current status and future prospects Designed biomaterials to mimic the mechanical properties of muscles Endometrial stem cell transplantation restores dopamine production in a parkinson's disease model Circadian-independent cell mitosis in immortalized fibroblasts Generation of pluripotent stem cells from eggs of aging mice CNS transplantation of purified human neural stem cells in neuronal ceroid lipofuscinoses: phase I trial IGF-1R regulation of colon cancer stem cells Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst Effects of aerobic exercise training on cognitive function and cortical vascularity in monkeys Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone Retargeted adenoviral cancer gene therapy for tumour cells overexpressing epidermal growth factor receptor or urokinase-type plasminogen activator receptor Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids c-Myc regulates transcriptional pause release Maternal circulating CD34+VEGFR-2+ and CD133+VEGFR-2+ progenitor cells increase during normal pregnancy but are reduced in women with preeclampsia Identification of select glucocorticoids as Smoothened agonists: Potential utility for regenerative medicine Mesenchymal stem cells protect breast cancer cells through regulatory T cells: role of mesenchymal stem cell-derived TGF-β XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification Metabolic oxidation regulates embryonic stem cell differentiation Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior Genome-wide meta-analyses identify multiple loci associated with smoking behavior Meta-analysis and imputation refines the association of 15q25 with smoking quantity Synovial fluid proteins differentiate between the subtypes of juvenile idiopathic arthritis Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection Progesterone induces adult mammary stem cell expansion Safety and feasibility of autologous bone marrow cellular therapy in relapsing-progressive Multiple Sclerosis Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells The effect of prenatal smoking exposure on adolescents' use of psychiatric drugs New loci associated with kidney function and chronic kidney disease Targeted gene deletions in C. elegans using transposon excision Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells HAMLET interacts with lipid membranes and perturbs their structure and integrity Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease Genomic profiling of sentinel lymph node breast cancer metastasis Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk Substitutions in woolly mammoth hemoglobin confer biochemical properties adaptive for cold tolerance p53-mediated hematopoietic stem and progenitor cell competition T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis Sex differences of chondrogenic progenitor cells in late stages of osteoarthritis In vivo evaluation of a tissue-engineered stem cell vascular graft Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation Control of mammary stem cell function by steroid hormone signaling Nerve growth factor promotes cardiac repair following myocardial infarction Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa Plant thymidine kinase 1: a novel efficient suicide gene for malignant glioma therapy Labeling human embryonic stem cell-derived cardiomyocytes with indocyanine green for noninvasive tracking with optical imaging: an FDA-compatible alternative to firefly luciferase A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations Gold nanocages as photothermal transducers for cancer treatment Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation Coronary arteries form by developmental reprogramming of venous cells MiDReG: A method of mining developmentally regulated genes using Boolean implications Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes Retinoic acid regulates differentiation of the secondary heart field and TGFβ-mediated outflow tract septation Geometric cues for directing the differentiation of mesenchymal stem cells Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects Using nanoparticle-filled microcapsules for site-specific healing of damaged substrates--creating a "repair-and-go" system Inactivation of both foxo and reaper promotes long-term adult neurogenesis in Drosophila Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds Genetic analysis of variation in transcription factor binding in yeast Variation in transcription factor binding among humans RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development Safety and efficacy of subretinal readministration of a viral vector in large animals to treat congenital blindness The basal ganglia communicate with the cerebellum A human gut microbial gene catalogue established by metagenomic sequencing Protein folding stability and dynamics imaged in a living cell Scaling laws of marine predator search behavior Human mammary epithelial cells exhibit a bimodal correlated random walk pattern Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele Lack of p21 expression links cell cycle control and appendage regeneration in mice Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles Computational prediction of neural progenitor cell fates Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity Generation of functional multipotent adult stem cells from GPR125+ germline progenitors Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene Endothelial cells are essential for the self-renewal and repopulation of notch-dependent hematopoietic stem cells Kinetics of antimicrobial peptide activity measured on individual bacterial cells using high-speed atomic force microscopy Leptin therapy in insulin-deficient type I diabetes miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia Hydrated xenogeneic decellularized tracheal matrix as a scaffold for tracheal reconstruction Innate immune lectins kill bacteria expressing blood group antigen Common genetic variants associated with breast cancer and mammographic density measures that predict disease Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development Haematopoietic stem cells derive directly from aortic endothelium during development Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks Risk of recurrent stroke, myocardial infarction, or death in hospitalized stroke patients Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis Computational prediction of neural progenitor cell fates TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI Gallstones play a significant role in Salmonella spp. gallbladder colonization and carriage Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosis Effects of carboxylic acids on nC60 aggregate formation Characterization of airborne particles during production of carbonaceous nanomaterials U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis Quorum-sensing-regulated virulence factors in Pseudomonas aeruginosa are toxic to Lucilia sericata maggots Molecular basis of the death-associated protein kinase–calcium/calmodulin regulator complex Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host Cancer stem cells from colorectal cancer-derived cell lines Coexistence of quiescent and active adult stem cells in mammals A nonviral minicircle vector for deriving human iPS cells Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival Cell fusion of bone marrow cells and somatic cell reprogramming by embryonic stem cells Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site Tinkering inside the organelle Dynamic changes in the human methylome during differentiation DNA heats up: energetics of genome ejection from phage revealed by isothermal titration calorimetry Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy Direct conversion of fibroblasts to functional neurons by defined factors Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer CRFR1 is expressed on pancreatic β cells, promotes β cell proliferation, and potentiates insulin secretion in a glucose-dependent manner Anucleate platelets generate progeny The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism Brainstem serotonergic deficiency in sudden infant death syndrome Regulation of alternative splicing by histone modifications G protein subunit Gα13 binds to integrin αIIbβ3 and mediates integrin "outside-in" signaling Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease Interaction between RasV12 and scribbled clones induces tumor growth and invasion Dual roles for perivascular macrophages in immune-to-brain signaling Altered gene expression and DNA damage in peripheral blood cells from Friedreich's Ataxia patients: cellular model of pathology Identification of a class of HCV inhibitors directed against the nonstructural protein NS4B AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α Transforming growth factor β-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway Glioma-associated cancer-initiating cells induce immunosuppression Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4 Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution Human stem cell delivery for treatment of large segmental bone defects COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform Calculating the potential for within-flight transmission of influenza A (H1N1) APOBEC3 proteins mediate the clearance of foreign DNA from human cells Analysis of dystrophin deletion mutations predicts age of cardiomyopathy onset in Becker Muscular Dystrophy Modeling disease in human ESCs using an efficient BAC-based homologous recombination system Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit Beyond the scalpel: targeting hedgehog in skin cancer prevention Hippocampal mean diffusivity and memory in healthy elderly individuals Production of cell-cell signalling molecules by bacteria isolated from human chronic wounds Restricted ethnic diversity in human embryonic stem cell lines Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori Alzheimer’s-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter High-performance genetically targetable optical neural silencing by light-driven proton pumps Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform Smoking, smoking cessation, and risk for type 2 diabetes mellitus: a cohort study CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts A role for the elongator complex in zygotic paternal genome demethylation Is survival better at hospitals with higher "end-of-life" treatment intensity? Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection The transcriptional network for mesenchymal transformation of brain tumours Dramatic increase in cortical thickness induced by femoral marrow ablation followed by a three-month treatment with PTH in rats Sex-dependent association of common variants of microcephaly genes with brain structure In vivo fluorescent detection of Fe-S clusters coordinated by human GRX2 Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient Real-time imaging reveals the single steps of brain metastasis formation Forever young: how to control the elongation, differentiation, and proliferation of cells using nanotechnology Blanes cells mediate persistent feedforward inhibition onto granule cells in the olfactory bulb Semilunar granule cells: glutamatergic neurons in the rat dentate gyrus with axon collaterals in the inner molecular layer Nonrandom local circuits in the dentate gyrus Representing information in cell assemblies: persistent activity mediated by semilunar granule cells Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages Receptor channel TRPC6 is a key mediator of notch-driven glioblastoma growth and invasiveness The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing Tumor self-seeding by circulating cancer cells Lipid-like materials for low-dose, in vivo gene silencing Bioartificial matrices for therapeutic vascularization Impaired hepatocyte regeneration in acute severe hepatic injury enhances effective repopulation by transplanted hepatocytes Long-term effects of bupivacaine on cartilage in a rabbit shoulder model The in vitro effects of bupivacaine on articular chondrocytes Patient-specific, time-varying predictors of post-ICU informal caregiver burden: the caregiver outcomes after ICU discharge project Adipose tissue regeneration Deciding fate in adverse times: sporulation and competence in Bacillus subtilis A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive mental retardation A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus Genomewide association study of leprosy An adequately robust early TNF-α response is a hallmark of survival following trauma/hemorrhage A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche Cell therapy of corneal diseases with umbilical mesenchymal stem cells Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells A novel inhibitor of DNA polymerase β enhances the ability of temozolomide to impair the growth of colon cancer cells A synergistic small-molecule combination directly eradicates diverse prion strain structures Donor statin treatment protects against severe acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs Targeting breast stem cells with the cancer preventive compounds curcumin and piperine GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice Imbalance between GABAergic and glutamatergic transmission impairs adult neurogenesis in an animal model of Alzheimer's Disease Engineered “smart” materials for improved cardiomyocyte differentiation Atypical Progeroid Syndrome due to heterozygous missense LMNA mutations Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension RanBPM has proapoptotic activities that regulate cell death pathways in response to DNA damage Induction of death receptor ligand-mediated apoptosis in epithelial ovarian carcinoma: The search for sensitizing agents Isolation of antagonists of antigen-specific autoimmune T cell proliferation Notch promotes radioresistance of glioma stem cells PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase δ Surgical stress-induced immune cell redistribution profiles predict short-term and long-term postsurgical recovery Haploid genetic screens in human cells identify host factors used by pathogens Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells Asymmetric deactivation of HIV-1 gp41 following fusion inhibitor binding In situ regulation of dc subsets and T cells mediates tumor regression in mice A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction MEMS-based 3D optical microendoscopy Innate immune and chemically triggered oxidative stress modifies translational fidelity Embryoid body formation of human amniotic fluid stem cells depends on mTOR Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis Defining the role of syndecan-4 in mechanotransduction using surface-modification approaches Progressive chondrocyte death after impact injury indicates a need for chondroprotective therapy High harvest yield, high expansion, and phenotype stability of CD146 mesenchymal stromal cells from whole primitive human umbilical cord tissue Wheelchair repairs, breakdown, and adverse consequences for people with traumatic spinal cord injury A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron transfer dissociation tandem mass spectrometry High throughput characterization of combinatorial histone codes Role of NMDA receptor–dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries Superselective intraarterial cerebral infusion of bevacizumab: a revival of interventional neuro-oncology for malignant glioma In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells In vivo, noninvasive, label-free detection and eradication of circulating metastatic melanoma cells using two-color photoacoustic flow cytometry with a diode laser Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adult mouse brain Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease MOR23 promotes muscle regeneration and regulates cell adhesion and migration Autologous CD34+ cell therapy for refractory angina: 12 month results of the phase II ACT34-CMI study Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells Adaptive force transmission in amoeboid cell migration Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6′-sulfated sialyl Lewis X Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats Autologous umbilical cord blood mononuclear cell transplantation preserves right ventricular function in a novel model of chronic right ventricular volume overload Self-assembling chimeric polypeptide–doxorubicin conjugate nanoparticles that abolish tumours after a single injection Epidemiological pathology of dementia: attributable-risks at death in the medical research council cognitive function and ageing study The heritability and genetics of frontotemporal lobar degeneration A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors Common variants at five new loci associated with early-onset inflammatory bowel disease Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells FoxO3 regulates neural stem cell homeostasis Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers Long-term controlled normoglycemia in diabetic non-human primates after transplantation with hCD46 transgenic porcine islets Novel synthetic porous and biodegradable bone cement for orthopaedic and craniofacial regeneration Cell stimulation with optically manipulated microsources Effective repair of traumatically injured spinal cord by nanoscale block copolymer micelles Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome TAp63 induces senescence and suppresses tumorigenesis in vivo Translating metabolic exchange with imaging mass spectrometry SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer An antibody-recruiting small molecule that targets HIV gp120 Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants improve recovery after cervical spinal cord injury Requirement of alpha(4)beta(1) and alpha(5)beta(1) integrin expression in bone-marrow derived progenitor cells in preventing endotoxin-induced lung vascular injury and edema in mice Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial–mesenchymal transition in colon and breast cancer cells The postsynaptic function of type II cochlear afferents Massive gliosis induced by interleukin-6 suppresses Ab deposition in vivo: evidence against inflammation as a driving force for amyloid deposition Lung cancer diagnostic and treatment intervals in the United States: a health care disparity? Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways T helper 17 cells promote cytotoxic T cell activation in tumor immunity Pten in stromal fibroblasts suppresses mammary epithelial tumors Functional repair of human donor lungs by IL-10 gene therapy Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network Loss of Lkb1 in adult β cells increases β cell mass and enhances glucose tolerance in mice Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells Directed single molecule diffusion triggered by surface energy gradients A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer Molecular aging and rejuvenation of human muscle stem cells Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling The Argus™ II retinal prosthesis improves the ability of subjects to perform a spatial task Development of a model system for retinogenesis from a highly enriched population of human embryonic stem cell-derived retinal progenitors Retinal transplantation improves vision in macular degeneration and retinitis pigmentosa patients LigluR-mediated visual cortical responses in the rd1 mouse model of retinitis pigmentosa Genetic diagnosis by whole exome capture and massively parallel DNA sequencing Nanoparticle-based bio-barcode assay redefines "undetectable" PSA and biochemical recurrence after radical prostatectomy Generation of induced pluripotent stem cells using recombinant proteins A chemical platform for improved induction of human iPSCs Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells Generation of functional ventricular heart muscle from mouse ventricular progenitor cells Stem cell therapies benefit Alport syndrome Marked induction of the helix-loop-helix protein Id3 promotes the γδ T cell fate and renders their functional maturation notch independent Saturation density of skin fibroblasts as a quantitative screen for human cancer susceptibility Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments GSK-3 is a master regulator of neural progenitor homeostasis Human DNA methylomes at base resolution show widespread epigenomic differences Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex Aldehyde dehydrogenase–expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells Thymic involution in amyotrophic lateral sclerosis Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis Genetic population structure analysis in New Hampshire reveals eastern European ancestry Epistasis and its implications for personal genetics Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice A mathematical model of ischemic cutaneous wounds Differentiation of human embryonic stem cells to a parathyroid-like phenotype Programming the detection limits of biosensors through controlled nanostructuring Lung cancer in never smokers: molecular profiles and therapeutic implications Lung cancer in never smokers: clinical epidemiology and environmental risk factors Lung cancer in never smokers: a call to action LysRS serves as a key signaling molecule in the immune response by regulating gene expression Transcriptional signature and memory retention of human-induced pluripotent stem cells Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective HLA-DR alleles in amyloid β-peptide autoimmunity: a highly immunogenic role for the DRB1*1501 allele Transoral endoscopic inner layer esophagectomy: management of high-grade dysplasia and superficial cancer with organ preservation Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer Gene expression profiling reveals new protective roles for vitamin C in human skin cells Regulation of vertebrate nervous system alternative splicing and development by an sr-related protein Genome-wide association reveals three SNPs associated with sporadic amyotrophic lateral sclerosis through a two-locus analysis Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases Injectable hydrogels for brain tissue regeneration after traumatic brain injury (TBI) C/EBP-alpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges Polymer-functionalized nanodiamond platforms as vehicles for gene delivery 14-3-3z cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition A luminal epithelial stem cell that is a cell of origin for prostate cancer Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia Epigenetic silencing of death receptor 4 mediates tumor necrosis factor–related apoptosis-inducing ligand resistance in gliomas On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells Oxidized lipids enhance RANKL production by T lymphocytes: Implications for lipid-induced bone loss Dual and opposing roles of primary cilia in medulloblastoma development Loss of Parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation Nanog is the gateway to the pluripotent ground state Modeling early retinal development with human embryonic and induced pluripotent stem cells Tight long-term dynamic doxycycline responsive nigrostriatal GDNF using a single rAAV vector Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis Emergent or just complex? Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells Production of hepatocyte-like cells from human amnion Naive rat amnion-derived cell transplantation improved left ventricular function and reduced myocardial scar of postinfarcted heart Magnetic tagging increases delivery of circulating progenitors in vascular injury A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations DNA focusing using microfabricated electrode arrays Waterborne synthetic adhesives modeled after the Sandcastle glue of P. californica A water-borne adhesive modeled after the sandcastle glue of P. californica Targeted capture and massively parallel sequencing of 12 human exomes A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy A role for the transcriptional repressor blimp-1 in CD8+ T cell exhaustion during chronic viral infection Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells Human RPE65 gene therapy for leber congenital amaurosis: persistence of early visual improvements and safety at 1 year Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain A granulocyte-macrophage colony–stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties Optical torques guide cell motility Cerebellothalamocortical connectivity regulates penetrance in dystonia Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell–derived lin–CD34+CD43+CD45+ progenitors A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth Tumor emergence is sensed by self-specific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells Tumor suppression by phospholipase C-β3 via SHP-1-mediated dephosphorylation of Stat5 Cell–cell interaction networks regulate blood stem and progenitor cell fate Phosphoproteomic analysis of human embryonic stem cells Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice Programming cells by multiplex genome engineering and accelerated evolution Sociodemographic differences in early access to liver transplantation services Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific antitumor vaccines in patients with metastatic melanoma: final report Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers MEK4 function, genistein treatment, and invasion of human prostate cancer cells Intrinsic light response of retinal horizontal cells of teleosts MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells Nanodiamond-insulin complexes as pH-dependent protein delivery vehicles MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein Critical role for caspase-8 in epidermal growth factor signaling Induction of stem cell gene expression in adult human fibroblasts without transgenes Identification of splenic reservoir monocytes and their deployment to inflammatory sites Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding An exploratory pathways analysis of temporal changes induced by spinal cord injury in the rat bladder wall: insights on remodeling and inflammation Amnion: a potent graft source for cell therapy in stroke Direct transdifferentiation of stem/progenitor spermatogonia into reproductive and nonreproductive tissues of all germ layers Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease XIAP discriminates between type I and type II FAS-induced apoptosis Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA Bcl6 mediates the development of T follicular helper cells Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections Psychoneuroimmunology--psychology’s gateway to the biomedical future N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis Regulated fluctuations in Nanog expression mediate cell fate decisions in embryonic stem cells Identification of genes conferring resistance to 5-fluorouracil Circulating osteogenic precursor cells in heterotopic bone formation Hearing improvement after Bevacizumab in patients with Neurofibromatosis Type 2 Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion A network model of a cooperative genetic landscape in brain tumors Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome Hematopoietic cytokines can instruct lineage choice Effect of ingested interferon-α on β-cell function in children with new-onset type 1 diabetes Plk1-mediated phosphorylation of topors regulates p53 stability Dependence of mouse embryonic stem cells on threonine catabolism A functional role for adult hippocampal neurogenesis in spatial pattern separation Immune blood biomarkers of Alzheimer disease patients High levels of circulating VEGFR2+ bone marrow–derived progenitor cells correlate with metastatic disease in patients with pediatric solid malignancies Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice Chd1 regulates open chromatin and pluripotency of embryonic stem cells HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation BRIT1/MCPH1 links chromatin remodelling to DNA damage response Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1 CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer HUMMR, a hypoxia- and HIF-1a–inducible protein, alters mitochondrial distribution and transport Understanding biophysicochemical interactions at the nano–bio interface Cancer mortality in patients with schizophrenia: an 11-year prospective cohort study Cell derived hierarchical assembly of a novel phosphophoryn-based biomaterial Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Resistance to age-dependent thymic atrophy in long-lived mice that are deficient in pregnancy-associated plasma protein A. Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control Directing cell motions on micropatterned ratchets The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis Formation of conjugated polymer brushes by surface-initiated catalyst-transfer polycondensation Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin The vascular basement membrane as “soil” in brain metastasis Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations Allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission Live-imaging of single stem cells within their niche reveals that a U3snoRNP component segregates asymmetrically and is required for self-renewal in Drosophila Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia A mechanism linking extra centrosomes to chromosomal instability CCR3 is a target for age-related macular degeneration diagnosis and therapy Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells Activation of tumor cell integrin αvβ3 controls angiogenesis and metastatic growth in the brain REL, encoding a member of the NF-kB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway Distinctive chromatin in human sperm packages genes for embryo development Global gene expression analysis of reactive stroma in prostate cancer Targeting tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in mice Repeated aerosol delivery of carboxyl-terminal modulator protein suppresses tumor in the lungs of K-rasLA1 mice Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages The role of Scgb1a1+ clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium Life and death by death receptors Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment Functional substitution by TAT-utrophin in dystrophin-deficient mice Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures Biomechanical regulation of blood vessel growth during tissue vascularization Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells Generation of pig-induced pluripotent stem cells with a drug-inducible system The aIRE1-XBP1 pathway of the unfolded protein response is required for adipogenesis Development of microfluidics as endothelial progenitor cell capture technology for cardiovascular tissue engineering and diagnostic medicine Gene expression profiling of preplate neurons destined for the subplate: genes involved in transcription, axon extension, neurotransmitter regulation, steroid hormone signaling, and neuronal survival Reciprocal responsiveness to interleukin-12 and interferon-a specifies human CD8+ effector versus central memory T-cell fates Delivery of adipose-derived precursor cells for peripheral nerve repair Phase III randomized trial of the chimeric anti-GD2 antibody ch14.18 with GM-CSF and IL2 as immunotherapy following dose intensive chemotherapy for high-risk neuroblastoma: Children’s Oncology Group (COG) study ANBL0032 Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein Simulation and prediction of the adaptive immune response to influenza A virus infection Implantable diagnostic device for cancer monitoring Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors Biomechanical forces promote embryonic haematopoiesis Hematopoietic stem cell development is dependent on blood flow Nest making and oxytocin comparably promote wound healing in isolation reared rats A new role for FGF2 as an endogenous inhibitor of anxiety Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II–induced aortic aneurysms Ube3a is required for experience-dependent maturation of the neocortex Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data Cotransplantation of mouse embryonic stem cells and bone marrow stromal cells following spinal cord injury suppresses tumor development Genes that mediate breast cancer metastasis to the brain Engineering three-dimensional cartilage- and bone-like tissues using human dermal fibroblasts and macroporous gelatine microcarriers Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil Stem cell therapy restores transparency to defective murine corneas Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39 Dendrimers as synthetic gene vectors: Cell membrane attachment Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery CD4+ CD25+ T cells control autoimmunity in the absence of B cells miR-375 maintains normal pancreatic α- and β-cell mass Cell–cell contact globally activates microRNA biogenesis Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2 Repair of the tympanic membrane with urinary bladder matrix Atomic force microscopy detects differences in the surface brush of normal and cancerous cells Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro LGMD 2D gene therapy restores alpha-sarcoglycan and associated proteins Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (sc) and tracks sc overpopulation during colon tumorigenesis Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling Parvalbumin neurons and gamma rhythms enhance cortical circuit performance Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation A computational model of the role of presenilin-1 and glycogen synthase kinase-3 in familial Alzheimer’s disease Single molecule–sensitive probes for imaging RNA in live cells Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal Molecular stages of rapid and uniform neuralization of human embryonic stem cells Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo Adenovirus encoding human platelet-derived growth factor-b delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use Protein-directed synthesis of highly fluorescent gold nanoclusters Oncolytic reovirus effectively targets breast cancer stem cells A functional screen to identify novel effectors of hematopoietic stem cell activity Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells Histone modifications at human enhancers reflect global cell-type-specific gene expression Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes Programmed subcellular release for studying the dynamics of cell detachment MERIT40 controls BRCA1–Rap80 complex integrity and recruitment to DNA double-strand breaks Molecular therapy of obesity and diabetes by a physiological autoregulatory approach Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia Differences in immune response may explain lower survival among older men with pneumonia Cancer-specific transgene expression mediated by systemic injection of nanoparticles Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration MicroRNA-125b is a novel negative regulator of p53 The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles A functional genomic screen identifies cellular cofactors of hepatitis C virus replication Common variants at ten loci modulate the QT interval duration in the QTSCD Study β1 integrin cytoplasmic domain residues selectively modulate fibronectin matrix assembly and cell spreading through talin and Akt-1 Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity Dendritic cell targeting of Bacillus anthracis protective antigen expressed by Lactobacillus acidophilus protects mice from lethal challenge Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease CD98hc facilitates B cell proliferation and adaptive humoral immunity Structural insights into the molecular organization of the S-layer from Clostridium difficile Identification of progenitor cells that contribute to heterotopic skeletogenesis Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta Can phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report A unified mathematical model for the prediction of controlled release from surface and bulk eroding polymer matrices ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing Gold nanorod/Fe3O4 nanoparticle "nano-pearl-necklaces" for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells Imaging intracellular viscosity of a single cell during photoinduced cell death New insights into the genetics of addiction BrafV600E cooperates with Pten loss to induce metastatic melanoma The neural origins of shell structure and pattern in aquatic mollusks Instant immunity through chemically programmable vaccination and covalent self-assembly Transcription factor Achaete Scute-Like 2 controls intestinal stem cell fate piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells Supervised risk predictor of breast cancer based on intrinsic subtypes Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and B-catenin stabilization Telomerase insufficiency in rheumatoid arthritis An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency Programmed assembly of 3-dimensional microtissues with defined cellular connectivity A fluidic device to study directional angiogenesis in complex tissue and organ culture models Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration Partial-wave microscopic spectroscopy detects subwavelength refractive index fluctuations: an application to cancer diagnosis The reciprocal coordination and mechanics of molecular motors in living cells Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines From donuts to drugs: nano-biotechnology evolution or revolution? A two-step mechanism for stem cell activation during hair regeneration Cardiac fibroblasts regulate myocardial proliferation through B1 integrin signaling Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves Directed evolution of adeno-associated virus to an infectious respiratory virus Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation A multi-center, randomized, clinical study to compare the effect and safety of autologous cultured osteoblast(Ossron™) injection to treat fractures Lumican inhibits collagen deposition in tissue engineered cartilage Atomic structure reveals the unique capsid organization of a dsRNA virus Superoxide dismutase 3, extracellular (SOD3) variants and lung function Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure Difference between the abilities of human Fc Y receptor-expressing CV-1 cells to neutralize American and Asian genotypes of Dengue Virus 2 Oct4-induced pluripotency in adult neural stem cells Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle Screening and characterization of surface-tethered cationic peptides for antimicrobial activity CXCL10 impairs B cell function and viability in diabetes through TLR4 signaling Epigenetic regulation of microRNAs in acute lymphoblastic leukemia Association of reactive oxygen species levels and radioresistance in cancer stem cells Controlling cell position in complex heterotypic 3D microtissues by tissue fusion Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains Nkx2–5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo An acellular matrix-bound ligand enhances the mobilization, recruitment and therapeutic effects of circulating progenitor cells in a hindlimb ischemia model Luminal flow patterns dictate arterial drug deposition in stent-based delivery Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study Biohybrid devices and encapsulation technologies for engineering a bioartificial pancreas The choice of anatomical site for islet transplantation Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment Infection-mimicking materials to program dendritic cells in situ Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals Metabolic dysregulation and adipose tissue fibrosis: the role of collagen VI Comparison of autologous full-thickness gingiva and skin substitutes for wound healing The role of tumor cell–derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity Model of genetic variation in human social networks Transient elastic support for vein grafts using a constricting microfibrillar polymer wrap Human embryonic stem cell differentiation toward regional specific neural precursors Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy Dynamic proteomics of individual cancer cells in response to a drug On the role of cell signaling models in cancer research Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus Axon regeneration requires a conserved MAP kinase pathway miRNA in situ hybridization in formaldehyde and EDC–fixed tissues Different T cell receptor signals determine CD8+ memory versus effector development Intravital imaging of metastatic behavior through a mammary imaging window Nanoscale imaging of molecular positions and anisotropies Photoactivatable mCherry for high-resolution two-color fluorescence microscopy T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe–/– mice Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia Programmed assembly of DNA-coated nanowire devices The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores HMGB1 mediates endogenous TLR2 activation and brain tumor regression Reduced COX-2 expression in aged mice is associated with impaired fracture healing A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification Near-infrared gold nanocages as a new class of tracers for photoacoustic sentinel lymph node mapping on a rat model Pick-and-place using chemically actuated microgrippers Tetherless thermobiochemically actuated microgrippers DNA repair gene polymorphisms and risk of pancreatic cancer Positive regulation of plasmacytoid dendritic cell function via Ly49Q recognition of class I MHC Prolonged continuous in vitro human platelet production using three-dimensional scaffolds Nuclear import is required for the pro-apoptotic function of the Golgi protein p115 Induced pluripotent stem cells from a spinal muscular atrophy patient Survey of the human pancreatic beta cell G1/S proteome reveals a potential therapeutic role for Cdk-6 and cyclin D1 in enhancing human beta cell replication and function in vivo Tissue-engineered skin containing mesenchymal stem cells improves burn wounds Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease SIRT6 links histone H3 lysine 9 deacetylation to NF-kB-dependent gene expression and organismal life span An adenoviral vector-based mucosal vaccine is effective in protection against botulism Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter Human calmodulin-like protein (CLP) expression in oral squamous mucosa and in malignant transformation Transcriptome sequencing to detect gene fusions in cancer AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice Dissociation of seizure traits in inbred strains of mice using the flurothyl kindling model of epileptogenesis In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny iPS cell generation using a single lentiviral stem cell cassette Neuronal activity–induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells Advancing systems biology for medical applications The role of the biochemical and biophysical environment in chondrogenic stem cell differentiation assays and cartilage tissue engineering Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche Development of a novel mouse glioma model using lentiviral vectors Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer Myocardial adeno-associated virus serotype 6–βARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure Microfluidic control of cell pairing and fusion Effects of cardiorespiratory fitness and cerebral blood flow on cognitive outcomes in older women Differential mobilization of subsets of progenitor cells from the bone marrow Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth Reversal of heroin neurobehavioral teratogenicity by grafting of neural progenitors Transplantation of neural progenitors enhances production of endogenous cells in the impaired brain The brain in the age of old: The hippocampal formation is targeted differentially by diseases of late life Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii Development of a portable therapeutic and high intensity ultrasound system for military, medical, and research use Fate tracing reveals the endothelial origin of hematopoietic stem cells Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy Tissue-specific genetic control of splicing: implications for the study of complex traits Tumor vasculature-targeted delivery of tumor necrosis factor-a Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis Starving neurons show sex difference in autophagy Multiplex protein assays based on real-time magnetic nanotag sensing A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart Nodal signalling is involved in left–right asymmetry in snails Murine bone marrow-derived mesenchymal stem cells as vehicles for interleukin-12 gene delivery into Ewing sarcoma tumors Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells β-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation Genetic defects in surfactant protein a2 are associated with pulmonary fibrosis and lung cancer Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes In vitro analog of human bone marrow from 3D scaffolds with biomimetic inverted colloidal crystal geometry Cultural cognition of the risks and benefits of nanotechnology Shared and distinct genetic variants in type 1 diabetes and celiac disease Non-myeloablative hematopoietic stem cell transplantation in older patients with AML and MDS: Results from the Center for International Blood and Marrow Transplant Research (CIBMTR) Common variants at 30 loci contribute to polygenic dyslipidemia Subdivisions of primary motor cortex based on cortico-motoneuronal cells Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation An obesity-associated FTO gene variant and increased energy intake in children Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression Reprogramming of murine and human somatic cells using a single polycistronic vector AAV2/1-TNFR:Fc gene delivery prevents periodontal disease progression Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells Delivery of apoptotic signal to rolling cancer cells: A novel biomimetic technique using immobilized TRAIL and E-selectin Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia Endochondral ossification is required for haematopoietic stem-cell niche formation Self-renewal and expansion of single transplanted muscle stem cells Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans Evaluating the safety and efficacy of anti-HIV transgenic cells in a humanized mouse model (NOD/SCIDγc–/–) for HIV stem cell gene therapy Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes Membrane shape as a reporter for applied forces Detection of functional haematopoietic stem cell niche using real-time imaging Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells Non-cell-autonomous effect of human SOD1G37R astrocytes on motor neurons derived from human embryonic stem cells Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair Sequential development of synapses in dendritic domains during adult neurogenesis Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture Cutting edge: a T-bet-independent role for IFN-/β in regulating IL-2 secretion in human CD4+ central memory T cells Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells Single-RNA counting reveals alternative modes of gene expression in yeast Blazing the trail from stem cell research to regenerative medicine Ascites specific inhibition of CD1d-mediated activation of natural killer T cells Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma Notch pathway modulation on bone marrow-derived vascular precursor cells regulates their angiogenic and wound healing potential Efficient tumour formation by single human melanoma cells Identification of a receptor required for the anti-inflammatory activity of IVIG A dynamic zone defines interneuron remodeling in the adult neocortex α-Catenin mediates initial E-cadherin-dependent cell–cell recognition and subsequent bond strengthening A novel flex-stretch-flow bioreactor for the study of engineered heart valve tissue mechanobiology Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice Stimulation of neural regeneration in the mouse retina A novel method for enrichment and selection of dopamine progenitor cells from human ES cells New ISSCR guidelines underscore major principles for responsible translational stem cell research Derivation of functional insulin-producing cell lines from primary mouse embryo culture Generating mESC-derived insulin-producing cell lines through an intermediate lineage-restricted progenitor line Association of genes involved in lipid metabolismperoxidation and risk of renal cancer in the Central European Renal Cancer Case-Control Study Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms Transplanted mouse embryonic stem-cell-derived motoneurons form functional motor units and reduce muscle atrophy Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice Generation of retinal stem cells and functional eyes from pluripotent cells Clinical transplantation of a tissue-engineered airway Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Endogenous VEGF is required for visual function: evidence for a survival role on Müller cells and photoreceptors Stable long-term donor engraftment following reduced-intensity hematopoietic cell transplantation for sickle cell disease The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology Cdk5 is essential for adult hippocampal neurogenesis The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder Putative dental pulp-derived stem/stromal cells promote proliferation and differentiation of endogenous neural cells in the hippocampus of mice The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid B-protein level in vivo Intravital imaging of metastatic behavior through a mammary imaging window H3K79 methylation profiles define murine and human MLL-AF4 leukemias A role for VEGF as a negative regulator of pericyte function and vessel maturation Electromagnetic interference (EMI) of implanted cardiac devices by MP3 player headphones Early treatment of high-risk chronic lymphocytic leukemia with alemtuzumab and rituximab Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro Myogenic endothelial cells purified from human skeletal muscle improve cardiac function after transplantation into infarcted myocardium Illumination controls differentiation of dopamine neurons regulating behavior Effects of direct transplantation of multipotent mesenchymal stromal/stem cells into the demyelinated spinal cord Foxl1 is a marker of bipotential hepatic progenitor cells in mice Mechanical and biological properties of nanoporous carbon membranes Harvesting the energy of cardiac motion to power a pacemaker Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis Human tissue-engineered heart valves based on umbilical cord blood derived progenitor cells as single cell source A role for VEGF as a negative regulator of pericyte function and vessel maturation Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes Structure of Seneca Valley Virus-001: an oncolytic picornavirus representing a new genus Wnt signaling mediates self-organization and axis formation in embryoid bodies A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation 5|[prime]|-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma Alternative isoform regulation in human tissue transcriptomes HITS-CLIP yields genome-wide insights into brain alternative RNA processing Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens Accordion-like honeycombs for tissue engineering of cardiac anisotropy The in vitro effects of bupivacaine on articular chondrocytes Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase–generated superoxide Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling Chemical engineering of mesenchymal stem cells to induce a cell rolling response Nf1-dependent tumors require a microenvironment containing Nf1+/−- and c-kit-dependent bone marrow Hedgehog signaling regulates brain tumor initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas Genome-wide association analysis reveals putative Alzheimer's Disease susceptibility loci in addition to APOE Engineering microRNA responsiveness to decrease virus pathogenicity Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system A conserved arginine containing motif crucial for the assembly and enzymatic activity of the Mixed Lineage Leukemia protein-1 core complex A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potential Serum inter-a-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury Glia are essential for sensory organ function in C. elegans Fault diagnosis engineering of digital circuits can identify vulnerable molecules in complex cellular pathways Gene expression profiles during in vivo human rhinovirus infection A fast, robust and tunable synthetic gene oscillator Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf expression Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development Notch signaling regulates mammary stem cell function and luminal cell-fate commitment Generation of a prostate from a single adult stem cell Network model of survival signaling in large granular lymphocyte leukemia DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes Cross-talk between GlcNAcylation and phosphorylation: Site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting Global reorganization of replication domains during embryonic stem cell differentiation Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin Centrosome misorientation reduces stem cell division during ageing Lgr5 marks cycling, yet long-lived, hair follicle stem cells Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells Mobilized hematopoietic stem cell yield depends on species-specific circadian timing HSP90β regulates rapsyn turnover and subsequent AChR cluster formation and maintenance Ikaros confers early temporal competence to mouse retinal progenitor cells Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity Nanoparticulate delivery of diphtheria toxin DNA effectively kills mesothelin expressing pancreatic cancer cells A role for macroautophagy in protection against 4-hydroxytamoxifen–induced cell death and the development of antiestrogen resistance Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease Higher-order cellular information processing with synthetic RNA devices In vivo cloning of artificial DNA nanostructures Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy Spinal cord injury reveals multilineage differentiation of ependymal cells Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling In vivo modeling and detection of the ovarian cancer vascular marker TEM1 Identification of white adipocyte progenitor cells in vivo Generation of pluripotent stem cells from adult human testis Repigmentation of vitiligo by transplantation of autologous melanocyte cells cultured on amniotic membrane TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation Oligopotent stem cells are distributed throughout the mammalian ocular surface Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy Generation of insulin-secreting islet-like clusters from human skin fibroblasts Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells—implications for pregnancy-induced protection against breast cancer Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer Targeted development of registries of biological parts Volumetric and ionic regulation during the in vitro development of a corneal endothelial barrier Ependymal stem cells divide asymmetrically and transfer progeny into the subventricular zone when activated by injury Quantitation of aurora kinase A gene copy number in urine sediments and bladder cancer detection Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics Induced pluripotent stem cells generated without viral integration Small-molecule inhibitors of microRNA miR-21 function Preventing growth of brain tumors by creating a zone of resistance Noncytotoxic lytic granule–mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Calcification of multipotent prostate tumor endothelium Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum Regulatory networks define phenotypic classes of human stem cell lines ES-cell derived hematopoietic cells induce transplantation tolerance Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium Embryonic stem cell therapy of heart failure in genetic cardiomyopathy Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate technique. Phase I trial of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results Regulatory networks define phenotypic classes of human stem cell lines In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway DYRK1A-dosage imbalance perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome The type I TGF-b receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner Genes mirror geography within Europe Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis In vivo reprogramming of adult pancreatic exocrine cells to B-cells HES-1 is involved in adaptation of adult human β-cells to proliferation in vitro Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation Integrins control the positioning and proliferation of follicle stem cells in the Drosophila ovary Senescence of activated stellate cells limits liver fibrosis Allogeneic endometrial regenerative cells: an "off the shelf solution" for critical limb ischemia? Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts Making insulin-deficient type 1 diabetic rodents thrive without insulin Biological properties and enucleation of red blood cells from human embryonic stem cells The rho-rock-myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells Interferon-α initiates type 1 diabetes in nonobese diabetic mice Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice A perivascular origin for mesenchymal stem cells in multiple human organs Transoral endoscopic fundoplication in the treatment of gastroesophageal reflux disease: the anatomic and physiologic basis for reconstruction of the esophagogastric junction using a novel device Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer Drug delivery with carbon nanotubes for in vivo cancer treatment Toll-like receptor 3 and geographic atrophy in age-related macular degeneration Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate Increase in endoplasmic reticulum stress–related proteins and genes in adipose tissue of obese, insulin-resistant individuals Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization Expression of ACE (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells Systems biology of the clock in Neurospora crassa Racial differences in the frequencies of HLA-specific B cells The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells Mouse development with a single E2F activator A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/BMP signaling during tooth and palate development Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma Tumor regression in cancer patients by very low doses of a T cell–engaging antibody Pre-clinical evaluation of a novel nanoemulsion-based hepatitis B mucosal vaccine Inhibition of human glutaminyl cyclase: A potential new treatment for AD PRDM16 controls a brown fat/skeletal muscle switch Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form shh-induced medulloblastoma GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein Bone marrow-derived mesenchymal stem cells ameliorate autoimmune enteropathy independently of regulatory T cells Association of a polymorphism near CREB1 with differential aversion processing in the insula of healthy participants Detecting skin cancer using volatile biomarkers Analyses of volatile organic compounds from human skin Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling A human embryonic stem cell line derived from a single blastomere of a 4-cell stage embryo Immobilized metal-affinity protein delivery via polyketal microparticles A new reactive oxygen species sensitive drug delivery vehicle for targeting oxidative stress Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells Current and future considerations in the use of mechanical circulatory support devices Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells Dual origin of tissue-specific progenitor cells in Drosophila tracheal remodeling Senescence of activated stellate cells limits liver fibrosis Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder Synthesis and antiproliferative activity of curcumin analogs Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function Phosphorylation of SNAP-23 by IκB kinase 2 regulates mast cell degranulation Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects Genome-scale DNA methylation maps of pluripotent and differentiated cells Dissecting direct reprogramming through integrative genomic analysis Cellular origins of adult human islet in vitro dedifferentiation Engineering robust and functional vascular networks in vivo with human adult and cord blood–derived progenitor cells T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 Germline mutations and variants in the succinate dehydrogenase genes in cowden and cowden-like syndromes Disease-specific induced pluripotent stem cells The effect of particle design on cellular internalization pathways A preliminary gene expression profile of acute graft-versus-host disease Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design Gene expression patterns in visual cortex during the critical period: Synaptic stabilization and reversal by visual deprivation Role of Sox-9, ER81 and VE-Cadherin in retinoic acid-mediated trans-differentiation of breast cancer cells Adaptive Foxp3+ regulatory t cell-dependent and -independent control of allergic inflammation A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein Bioresorbable hyaluronic acid hydrogels for tissue engineering applications Catalytic antibodies to HIV: Physiological role and potential clinical utility Calcium control of endocytic capacity at a CNS synapse Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles Miniaturized probe for femtosecond laser microsurgery and two-photon imaging An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression Antisense transcripts are targets for activating small RNAs Statin treatment of adult human glial progenitors induces PPARΎ-mediated oligodendrocytic differentiation Multiphoton fabrication of chemically responsive protein hydrogels for microactuation Large-scale analysis of gene clustering in bacteria Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating escs A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's Disease PANIC–ATTAC, a mouse model for inducible and reversible β cell ablation Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1 Targeting mutant p53 protein and tumor vasculature: An effective combination therapy for advanced breast tumors A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration GHRH improves survival and quality of life of companion dogs with cancer Protein−protein interaction detection in vitro and in cells by proximity biotinylation DNA packaging via combinative self-assembly Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells The B cell antigen receptor and overexpression of MYC can cooperate in the genesis of B cell lymphomas Intra-abdominal vagal blocking (VBLOC therapy): Clinical results with a new implantable medical device Dunking doughnuts into cells—selective cellular translocation and in vivo analysis of polymeric micro-doughnuts IRF4 addiction in multiple myeloma Polygenes, risk prediction, and targeted prevention of breast cancer Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse IL1RL1-IL18R1-IL18RAP-SLC9A4 and CARD9 loci are susceptibility factors for both Crohn’s disease and ulcerative colitis Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation Enhanced chondrocyte densities on carbon nanotube composites: The combined role of nanosurface roughness and electrical stimulation Evaluating suppression of nonsense mutations by aminoglycoside antibiotics as an intervention for vision loss in type I Usher syndrome Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA Blocking TGF-–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering Fatty acid synthase is upregulated during HCV infection and regulates HCV entry and production Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system Bmi1 is expressed in vivo in intestinal stem cells Shear stress improves adult stem cell attachment to vascular basement membrane components via upregulation of α5ß1integrin expression Inhalable siRNA: potential as a therapeutic agent in the lungs Cooperation of two MRNA-binding proteins drives metabolic adaptation to iron deficiency Cortical control of a prosthetic arm for self-feeding The ground state of embryonic stem cell self-renewal Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond Small-molecule activation of neuronal cell fate Neurons born in the adult dentate gyrus form functional synapses with target cells Defining the incidence of cardiorespiratory instability in patients in step-down units using an electronic integrated monitoring system Regional anatomic and age effects on cell function of human adipose-derived stem cells Increased plasma interleukin-6 in donors is associated with lower recipient hospital-free survival after cadaveric organ transplantation Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS) cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo Establishment of mouse embryonic stem cell-derived erythroid progenitor cell lines able to produce functional red blood cells Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation Osteolineage niche cells initiate hematopoietic stem cell mobilization Absorbent microbicidal wound dressing material with protease inhibition properties Functional genomic screen reveals genes involved in lipid-droplet formation and utilization Microparticle-mediated delivery of morphogenic factors within embryoid bodies Lysine-derived urethane surgical adhesive prevents seroma formation in a canine abdominoplasty model Repair of iatrogenic sphincter damage and urinary incontinence by autologous skeletal muscle derived cells (mdc) Transurethral ultrasound guided injection of autologus myo- and fibroblasts in incontinent men: 2 year data Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease Ex vivo expansion of cord blood nk cells with in vivo efficacy against acute myeloblastic and lymphoblastic leukemias The epithelial-mesenchymal transition generates cells with properties of stem cells Label-retaining cells of the bladder: candidate urothelial stem cells Latent stem and progenitor cells in the hippocampus are activated by neural excitation Endochondral bone tissue engineering using embryonic stem cells Expression of an estrogen receptor agonist in differentiating osteoblast cultures Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules Genetic approaches identify adult pituitary stem cells Safety and efficacy of gene transfer for Leber's Congenital Amaurosis Multiple genetic loci for bone mineral density and fractures Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation Fibronectin bridges monocytes and reticulocytes via integrin α4β1 Efficacy and safety of renal tubule cell therapy for acute renal failure Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells A novel magnetic approach to enhance the efficacy of cell-based gene therapies Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency Identification and characterization of cancer stem cells in ovarian cancer In vivo immunogold labeling confirms large-scale chromatin folding motifs Akt requires glucose-mediated regulation of bcl-2 family members to inhibit cell death Local delivery of gene vectors from bare-metal stents by use of a biodegradable synthetic complex inhibits in-stent restenosis in rat carotid arteries Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes Translational systems biology of inflammation A novel flex-stretch-flow bioreactor for the study of engineered heart valve tissue mechanobiology HDAC4 and PCAF bind to cardiac carcomeres and play a role in regulating myofilament contractile activity Minute dosages of aVB3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits Musashi1 regulates mammary progenitor cell expansion through activation of the Wnt and Notch pathway Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons Cardiogenic small molecules that enhance myocardial repair by stem cells Lifetime probabilities of hematopoietic stem cell transplantation in the U.S. Nucleofection mediates high-efficiency stable gene knockdown and transgene expression in human embryonic stem cells Noninvasive delivery of gene targeting probes to live brains for transcription MRI Memory enhancement induced by hypothalamic/fornix deep brain stimulation Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration A combinatorial library of lipid-like materials for delivery of RNAi therapeutics Arthroscopic replacement of massive, irreparable rotator cuff tears using a graftjacket allograft: technique and preliminary results Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo Origin and progeny of reactive gliosis: a source of multipotent cells in the injured brain Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation Contractile smooth muscle cells derived from hair-follicle stem cells PAX4 enhances beta-cell differentiation of human embryonic stem cells Cavity-enhanced optical frequency comb spectroscopy: application to human breath analysis Delayed rectifier and A-type potassium channels associated with Kv 2.1 and Kv 4.3 expression in embryonic rat neural progenitor cells Sequence- and target-independent angiogenesis suppression by siRNA via TLR3 Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain An extended transcriptional network for pluripotency of embryonic stem cells Stem cells from human fat as cellular delivery vehicles in an athymic rat posterolateral spine fusion model In vivo correction of a Menkes disease model using antisense oligonucleotides Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular B-amyloid deposit in Alzheimer mice Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits A comprehensive platform for ex vivo t-cell expansion based on biodegradable polymeric artificial antigen-presenting cells Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a Systemic vesicular stomatitis virus selectively destroys multifocal glioma and metastatic carcinoma in brain Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing The molecular etiology of breast cancer: evidence from biomarkers of risk A new arena virus in a cluster of fatal transplant-associated diseases Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration Rapid appearance and local toxicity of amyloid-B plaques in a mouse model of Alzheimer's disease Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2 Transparent adult zebrafish as a tool for in vivo transplantation analysis Lentiviral delivered VRX496 long antisense sequences exerts molecular pressure on HIV-1 in human subjects Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases Hematopoiesis and immunity of HOXB4-transduced embryonic stem cell–derived hematopoietic progenitor cells Self-assembly of large and small molecules into hierarchically ordered sacs and membranes Independent evolution of an antiviral TRIMCyp in rhesus macaques Stimuli-responsive polymer nanocomposites inspired by the sea cucumber dermis Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke model Transplanted endothelial cells repopulate the liver endothelium and correct the phenotype of hemophilia A mice The transition from stiff to compliant materials in squid beaks ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration Autologous transplantation of endothelial progenitor cells attenuates acute lung injury in rabbits Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1 Gene expression changes in children with autism Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation DNA double helices recognize mutual sequence homology in a protein free environment NFATc1 balances quiescence and proliferation of skin stem cells P-selectin–coated microtube for enrichment of CD34+ hematopoietic stem and progenitor cells from human bone marrow Investigating the feasibility of stem cell enrichment mediated by immobilized selectins Capture and enrichment of CD34-positive haematopoietic stem and progenitor cells from blood circulation using P-selectin in an implantable device Human embryonic stem cell derivation from poor-quality embryos Generation of biologically contained Ebola viruses Characterization of transplanted green fluorescent protein+ bone marrow cells into adipose tissue Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia Identification of cells initiating human melanomas Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring Functional skeletal muscle regeneration from differentiating embryonic stem cells Nanomagnetic actuation of receptor-mediated signal transduction Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome Testing protocols in the intensive care unit--complex trials of complex interventions for complex patients Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone A comparison of bare-metal and drug-eluting stents for off-label indications Cancer stem cells with genetic instability: the best vehicle with the best engine for cancer Genome-wide transcriptional analysis of the human cell cycle identifies genes differentially regulated in normal and cancer cells Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery Recurrent 16p11.2 microdeletions in autism Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory t cells to avoid immune detection Review of U.S. medical device regulation The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves Human embryonic stem cell lines generated without embryo destruction Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart Early intramedullary femoral fixation versus external fixation in polytrauma patients at risk for systemic complications: a prospective randomized controlled multicenter study Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNAi Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury The potential of umbilical cord blood multipotent stem cells for nonhematopoietic tissue and cell regeneration Gene therapy reduces ethanol intake in an animal model of alcohol dependence Acute exposure to a moderate strength magnetic field reduces edema formation in rats Correction of Fragile X syndrome in mice Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma Effect of chemistry on thermo-mechanical shape-memory properties of acrylate networks Designing shape memory polymers networks for biomedical applications Atomistic characterization of the elastic bending behavior of metallic nanowires Modulating neuronal responses by controlled integration of acetylcholine-like functionalities in biomimetic polymers Reprogramming of human somatic cells to pluripotency with defined factors Imaging of mesenchymal stem cell transplant by bioluminescence and PET Three-dimensional cellular microarray for high-throughput toxicology assays HLA homozygous stem cell lines derived from human parthenogenetic blastocysts Unique dielectric properties distinguish stem cells and their differentiated progeny Improved cell survival in infarcted myocardium using a novel combination transmyocardial laser and cell delivery system Development of a tissue-engineered vascular graft combining a biodegradable scaffold, muscle-derived stem cells and a rotational vacuum seeding technique Isolation of rare circulating tumour cells in cancer patients by microchip technology Stem cell augmented reconstruction: a new hope for reconstruction after breast conservation therapy Identification of small molecules from human embryonic stem cells using metabolomics Comparable outcomes after nonmyeloablative hematopoietic cell transplantation with unrelated and related donors Safety of MGMT gene transfer into hematopoietic progenitors: a phase I clinical trial using retroviral gene transfer of G156A MGMT to protect hematopoiesis during BG plus alkylating agent treatment of advanced malignancies Restoration of human dystrophin following transplantation of exon-skipping-engineered DMD patient stem cells into dystrophic mice Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues Mutation in glycerol-3-phosphate dehydrogenase 1–like gene (gpd1-l) decreases cardiac NA+ current and causes inherited arrhythmias Choosing among living-donor and cadaveric livers Endometrial regenerative cells: a novel stem cell population Evidence for skeletal progenitor cells in the degenerate human intervertebral disc Neural stem cells improve memory in an inducible mouse model of neuronal loss Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation Skin-derived precursors generate myelinating schwann cells that promote remyelination and functional recovery after contusion spinal cord injury Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-b1 Prospective identification of myogenic endothelial cells in human skeletal muscle A novel multiparametric flow cytometry-based cytotoxicity assay simultaneously immunophenotypes effector cells: Comparisons to a 4 h (51)Cr-release assay Long-term propagation of distinct hematopoietic differentiation programs in vivo Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death Carbon nanotube sensors for exhaled breath components Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes Understanding the inflammatory cytokine response in pneumonia and sepsis Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in subacute myocardial infarction Directed engineering of umbilical cord blood stem cells to produce C-peptide and insulin Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1βXAT mouse model of arthritis by intraarticular induction of μ-opioid receptor into the temporomandibular joint The healing effects of autologous platelet gel on acute human skin wounds Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy Developmental reprogramming after chromosome transfer into mitotic mouse zygotes Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer From Baghdad to Germany: use of a new pumpless extracorporeal lung assist system in two severely injured us soldiers Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress A role for cell sex in stem cell–mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency Environmentally sensitive gels assembled through protein-polysaccharide interactions Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation Stem and progenitor cells in skeletal muscle development, maintenance, and therapy Fiber kinematics of small intestinal submucosa under biaxial and uniaxial stretch Strategies for reducing the door-to-balloon time in acute myocardial infarction Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy Craniofacial tissue engineering by stem cells Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrix Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer In situ labeling of immune cells with iron oxide particles: An approach to detect organ rejection by cellular MRI Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis Differential myocardial infarct repair with muscle stem cells compared to myoblasts Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study Mouse fetal liver cells in artificial capillary beds in three-dimensional four-compartment bioreactors Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function The vascular wall as a source of stem cells Outcomes 18 months after the first human partial face transplantation Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus Towards improved artificial lungs through biocatalysis Integrating bench to operating room: journey of a clinician-scientist Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in Parkinsonian mice Tissue-engineered autologous bladders for patients needing cystoplasty Nerve regeneration promoted in a tube with vascularity containing bone marrow-derived cells